Can G-C Hoogsteen-wobble pairs contribute to the stability of d(G{middle dot}C-C) triplexes?
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چکیده
منابع مشابه
Can G-C Hoogsteen-wobble pairs contribute to the stability of d(G. C-C) triplexes?
Quantum mechanics, molecular dynamics and statistical mechanics methods are used to analyze the importance of neutral Hoogsteen-wobble G.C pairing in the stabilization of triple helices based on the poly-(G.C-C) trio at neutral pH and low ionic strength. In spite of the existence of a single hydrogen bond, the Hoogsteen-wobble G.C pair is found to be quite stable both in gas phase and solvated ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1999
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/27.11.2248